Bibliography

Cera, Lee M. (DVM), Heggers, John P. (PhD, MT[AMT]), Hafstrom, William J. (MD), & Robson, Martin C. (MD). (1982, July/August). Therapeutic protocol for thermally injured animals and its successful use in an extensively burned Rhesus monkey. Journal of the American Animal Hospital Association,18, 633-638.

Abstract: This article from the University of Chicago Burn Center, is exceptional because the 70% burns received accidentally by this monkey should have been fatal, but the animal was not only saved but quickly returned to good health by treatment, the primary part of which was by Aloe vera.

Cera, Lee M. (DVM), Heggers, John P. (PhD), Robson, Martin C. (MD), & Hafstrom, William J. (MD). (1980, September/October). The therapeutic efficacy of Aloe vera cream in thermal injuries: Two case reports. Journal of the American Animal Hospital Association,16, 768-772.

Abstract: This report by the University of Chicago Burn Center is about two dogs, both mixed shepherds, who were accidentally burned over such a large portion of their bodies that ordinary treatment would have been considered nearly futile. The very successful use of an Aloe vera cream is carefully documented.

Cheney, Ralph H. (ScD). (1970). Aloe drug in human therapy. Quarterly Journal of Crude Drug Research,10, 1523-1530.

Abstract: Briefly discusses history, botany, parts used and production, chemistry, medical evaluation and experimentation of Aloe as it relates to x-ray and other thermal injuries and skin diseases.

Cheney, Ralph H. (ScD). (1970-1971). A cosmetic from a house plant. Brooklyn Botanical Garden, Record: Plants and Gardens,26(4), 19.

Cheney, Ralph H. (ScD). (1972). Phytotherapeutic medication value of 15 flowering plants. Acta Phytotherapy,19(5), 83.

Cherikchi, L. Ye. (N.D.). On the stability of therapeutic effect in treatment of eye diseases with Aloe extract electrophoresis (results of late observations). In Aloe Vera: New Scientific Discoveries by Max Skousen, 102-105.

Abstract: Therapeutic effect obtained in treatment of various eye diseases with aloe extract electrophoresis, is persistent. The effect of repeated courses of treatment with aloe extract electrophoresis is attended most commonly by further improvement in the conditions of the eyes.

Chikalo, I., & Bolovyeve, V. (N.D.). The small intestine’s function effected by Aloe extract. Extract of Aloe, Supplement to Clinical Data. Moscow, USSR: Medexport, Ukrainian SSR Research Institute of Eye Diseases and Tissue Therapy.

Abstract: Aloe extract may be recommended for stimulating the secretory function of the small intestine.

Chinnah, A., et al. (1992). Antigen dependent adjuvant activity of a polydispersed β-(1-4)-linked acetylated mannan (acemannan). Vaccine,10(8), 551-557.

Chithra, P., Sajithlal, G.B., & Chandrakasan, Gowri. (1998, January). Influence of Aloe vera on the glycosaminoglycans in the matrix of healing dermal wounds in rats. Journal of Ethnopharmacology,59(3), 179-186.

Abstract: It was observed that Aloe vera increased the collagen content of the granulation tissue, as well as its degree of cross linking as seen by increased aldehyde and decreased acid solubility. The group consuming Aloe vera indicated enhanced levels of type III collagen.

Chithra, Pandarinathan, Sajithlal, G. B., & Chandrakasan, Gowri. (1998, April). Influence of Aloe vera on collagen characteristics in healing dermal wounds in rats. Molecular and Cellular Biochemistry, 181, 71-76.

Chopra, R. N., & Ghosh, N. N. (1938). Chemische untersuchung der indischen Aloearten Aloe vera, Aloe India, Boyle. Archiv der Pharmazie,276, 348-350.

Chopra, R. N., Nayar, S. L., & Chopra, I. C. (1956). Glossary of Indian Medicinal Plants. Council of Scientific and Industrial Research, New Delhi.

Clarke, Jane. (2004, April 25). The potted physician: Body foods by Britain's leading nutrition expert. The Mail on Sunday. London, England.

Abstract: General discussion of how Aloe helps disease.

Coats, B. C. (1979). The silent healer: A modern study of Aloe vera. Garland, Texas: author.

Cock, F. William (MD). (1918, September 7). Aloes as a local sedative. The British Medical Journal,2, 256.

Cole, H. N. (MD), & Chen, K. K. (MD). (1943, February). Aloe vera in oriental dermatology. Archives of Dermatology and Syphilology, 47, 250.

Abstract: Brief history of oriental dermatological use of Aloe.

Collins, C. E. (1935, June). Alvagel as a therapeutic agent in the treatment of Roentgen and radium burns. The Radiological Review and Chicago Medical Recorder, 57, 137f.

Collins, C. E. (DDS, MD), & Collins, Creston (MS). (1935, March). Roentgen dermatitis treated with fresh whole leaf of Aloe vera. American Journal of Roentgenology, 33(3), 396-397.

Abstract: Fresh Aloe vera used for x-ray dermatitis. This article by Dr. Creston Collins and his father was the landmark report, creating waves of interest throughout the world among medical science. Since the new wonder treatment of roentgen rays had some tragic side effects, the ancient and often scoffed at “Medicine Plant” provided the only workable solution for many cases.

Coombe, Deirdre R., & Rider, Christopher C. (1989). Lymphocyte homing receptors cloned a role for anionic polysaccharides in lymphocyte adhesion. Immunology Today,10(9), 289-291.

Cope, Oliver. (1948) .The burn problem. Advances in Military Medicine,1, Chapter XII, 149-154.

Abstract: Pearl Harbor, World War II, and other burn disasters prompted this discussion of possible burn treatments.

Crewe, J. E. (MD). (1937). The external use of Aloes. Minnesota Medicine, 20, 670-673.

Abstract: Aloe treatment for palmar eczema, pruritus vulva, external ulcers, poison ivy and burns.

Crewe, J. E. (MD). (1939, January 6). Aloes in the treatment of burns and scalds. Minnesota Medicine,22, 538-539.

Abstract: This method has proved so simple and the results have been so satisfactory, that I have not used any other treatment for burns since the spring of 1935. I employ an ointment of which the active ingredient is Aloe.

Crosswhite, F. S., & Crosswhite, C. D. (1984). Aloe vera: Plant symbolism and the threshing floor. Desert Plants,6, 43-50.

Cutak, L. (1937). Aloe vera as a remedy for burns. Missouri Botanical Garden Bulletin,25, 169-174.

Czarapata, B. J. (1995, October). Whole-leaf Aloe vera capsules in interstitial cystitis, painful bladder syndrome, chronic pelvic pain, and nonbacterial prostatitis: A double-blind, placebo-controlled crossover trial using Desert Harvest Aloe vera at the Urology Wellness Center, Rockville, Maryland. Proceedings of the NIDDK Scientific Symposium, San Diego, California. National Institutes of Health, Rockville, Maryland.

Abstract: Because of the promising anecdotal findings of interstitial cystitis (IC) patients who had tried Desert Harvest's whole-leaf, freeze-dried Aloe vera capsules, the Urology Wellness Center (UWC) in Rockville, Maryland, designed a double-blind, placebo-controlled clinical trial of this highly concentrated form of the Aloe vera plant in 13 IC/PBS patients. The study included three months of placebo followed by three months of Aloe vera or vice versa, depending on randomization. The study included a cross-over segment, with each patient receiving both substances at some point during the study and acting as her/his own control. The patients were assigned control numbers randomized by computer, and the products were shipped directly to the patient every month by the blinded manufacturer. The primary objective of the study was to monitor the safety and efficacy of Desert Harvest's concentrated whole-leaf, freeze-dried Aloe vera capsules in the management of the symptoms of IC/PBS. The symptoms that were monitored included urinary frequency, nocturia, dysuria, urgency, and suprapubic pain. Response to therapy was monitored by Quality-of-Life Assessment, IC Symptom/Problem Index, Health Status Questionnaire, and 24-Hour Voiding Diary. Of the 13 patients who were recruited for the study, 8 completed the full six months of the trial. Of the 8 patients who completed the study, 7 patients received relief from at least some of their symptoms of pelvic pain, frequency of urination, pressure, or nocturia (87.5%). Four patients experienced significant relief from all or most of their symptoms (50%). Only one patient had no response after completing all six months of the study (12.5%).

Dallas Micro-Assay Service. (1971, June 2). A test on Aloe vera powder.

Danhof, Ivan E. (PhD, MD). (Autumn/Winter). Aloe leaf handling and constituent variability. Aloe Today, 12-15.

Abstract: The best aloe is a preparation which maximizes the desired constituents, minimizes any ingredient with negative effects, maintains the constituents in an unaltered and active form, preserves the actions and benefits, and is present in the final product in amounts which, indeed, can bring about the desired result when the product is used as recommended. The type of aloe leaf constituent desired can be obtained by various handling, processing and preserving systems; the ultimate use determining the best approaches to be utilized. Whole-leaf and "cold process" recommended.

Danhof, Ivan E. (PhD, MD). Internal uses of Aloe vera.

Abstract: Aloe used in intestinal disorders, atherosclerosis and coronary hearth disease, anti-cancer actions, immunity,

Danhof, Ivan (PhD, MD). (1991, July). Potential benefits from orally-ingested internal Aloe vera gel. Presented to the International Aloe Science Council 10 th Annual Aloe Scientific Seminar.

Abstract: Evidence will be presented that suggests increasing credibility for the benefits of ingested aloe gel.

Danhof, Ivan (MD, PhD). (N.D.). The fundamentals.

Abstract: Dr. Danhof is regarded by many as the leading authority on the Aloe vera plant. This paper gives the fundamentals of how the polysaccharide molecules help the body in the healing process.

Danhof, Ivan E. (PhD, MD). (N.D.). Position statement on polysaccharides.

Abstract: Discourages the use of the term mucopolysaccharides and encourages the use of the term polysaccharides when discussing Aloe vera.

Davis, Robert. (1997) Polysaccharide: The magic bullet. Inside Aloe, The International Aloe Science Council, Inc.

Davis, Robert H. (PhD). (1992, Autumn). Comments on the Aloe leaf. Aloe Today.

Abstract: General comments about Aloe including the structure of the leaf, how Aloe vera is made, skin penetration by mucilage and aloe vera, the aloe leaf assay, and the aloe vera cell.

Davis, Robert H. (PhD) (N.D.). The conductor-orchestra concept of Aloe vera. Cosmetics and Toiletries, 21-24.

Abstract: "The Conductor-Orchestra Concept" was developed to better define the relationships that exist among over 200 biologically active compounds within Aloe vera. One of these molecules, a polysaccharide, acts as the conductor and leads a symphony composed of these 200+ biologically active compounds.

Davis, Robert H. (PhD), Di Donato, Joseph J. (BA, BS), Hartman, Glenn M. (BS), & Haas, Richard C. (BA). (1992). Mannose-6-phosphate: Anti-inflammatory and wound healing activity of a growth substance in Aloe vera. Submitted for 1993 William J. Stickle Award.

Abstract: This study attempts to define the role of the two major sugar constituents in the Aloe plant, mannose and glucose. We analyzed these sugars in the phosphorylated form. The significance of this study lies in the ability of the phosphorylated sugars to fit the growth factor receptors on the surface of the fibroblast.

Davis, Robert H. (PhD), Di Donato, Joseph J. (BA, BS), Hartman, Glenn M. (BS), & Haas, Richard C. (BA). (1994, February). Anti-inflammatory and wound healing activity of a growth substance in Aloe vera. Journal of the American Podiatric Medical Association, 84(2), 77-81.

Abstract: Aloe vera improves wound healing and inhibits inflammation. Since mannose-6-phosphate is the major sugar in the Aloe gel, the authors examined the possibility of its being an active growth substance. Mice receiving 300 mc/kg of mannose-6-phosphate had improved wound healing over saline controls. This dose also had anti-inflammatory activity. The function of mannose-6-phosphate in A. vera is discussed.

Davis, Robert H. (PhD), Kabbani, Joseph M. (BS), & Maro, Nicholas P. (BS). (1987, April). Aloe vera and wound healing. Journal of the American Podiatric Medical Association, 77(4), 165-169.

Abstract: The authors present a study of the wound healing effects of Aloe vera. Special emphasis is given to combined RNA and vitamin C with Aloe because of their effectiveness against arthritis. Consideration is given to anthraquinones because their influence is not clearly understood. As a result of the preliminary findings in the study, the authors recommend Aloe for the treatment of wounds.

Davis, Robert H. (PhD), Leitner, Mark G. (RPh), & Russo, Joseph M. (BA). (1987, November). Topical anti-inflammatory activity of Aloe vera as measured by ear swelling. Journal of the American Podiatric Medical Association, 77(11), 610-612.

Abstract: The authors believe that this study provides a major breakthrough for Aloe and an effective treatment against inflammation for podiatrists.

Davis, Robert H. (PhD), Leitner, Mark G. (RPh), & Russo, Joseph M. (BA). (1988, February). Aloe vera - a natural approach for treating wounds, edema, and pain in diabetes. Journal of the American Podiatric Medical Association,78(2), 60-68.

Abstract: In this research project, the authors extrapolate their earlier findings, and better characterize Aloe vera as a therapeutic alternative for physicians to consider. They attempt to evaluate A. vera as an effective treatment for some of the most critical manifestations of diabetes.

Davis, Robert H. (PhD), Leitner, Mark G. (RPh, DPM), Russo, Joseph M. (DPM), & Byrne, Megan E. (BS). (1989, November). Wound healing: Oral and topical activity of Aloe vera. Journal of the American Podiatric Medical Association, 79(11), 559-562.

Abstract: The influence of Aloe vera, orally and topically, on wound healing was studied. These data suggest that A. vera is effective by both oral and topical routes of administration.

Davis, Robert H., Leitner, Mark G., Russo, Joseph M., & Matro, Nicholas P. (1987). Biological activity of Aloe vera. Med. Sci. Res, 15, 235.

Abstract: Our laboratory has shown that Aloe vera (Aloe barbadensis) was effective against adjuvant induced arthritis. There are no known side effects of the plant gel. In the present study, we attempted to show the comparative biological activity of Aloe vera as measured by standard anti-inflammatory tests: polymorphonuclear leukocyte infiltration, mustard induced edema, anti-fibrosis and wound healing.

Davis, Robert H. (PhD), Parker, William L. (BA), & Merdock, Douglas P. (Bsc). (1991, January). Aloe vera as a biologically active vehicle for hydrocortisone acetate. Submitted for the 1989 William J. Stickel Awards.

Abstract: This study attempts to use Aloe vera with hydrocortisone acetate to improve the effectiveness of this type of therapy. Inflammation is a major component of many of the conditions treated by the podiatrist. The significance of this study lies in the ability to increase steroid potency by using a natural substance.

Davis, Robert H. (PhD), Rosenthal, Kenneth Y., Cesario, Linda R., & Rouw, Gregory A. (1989, August). Processed Aloe vera administered topically inhibits inflammation. Journal of the American Podiatric Medical Association,79(8), 395-397.

Abstract: Aloe vera preparations were evaluated for topical anti-inflammatory activity using the croton oil-induced edema assay. These results may be used as a baseline to assess the biologic activity of A. vera in the treatment of inflammation by podiatric physicians.

Davis, Robert H. (PhD), Shipiro, Eugene, & Agnew, Patrick S. (1985, May). Topical effect of Aloe with ribonucleic acid and vitamin C on adjuvant arthritis. Journal of the American Podiatry Association, 75(5), 229-237.

Abstract: The anti-inflammatory and anti-arthritic topical activity of combined ascorbic acid, aloe extract, and RNA in hydrophilic cream were evaluated in this study. The results may provide an effective topical treatment for rheumatoid arthritis.

 

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