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[Full articles with abstracts are available when there is a hyperlink as part of the reference. Just click on the blue link to read more.]


Grindlay, D. (1985a). Medical use of Aloe vera. General Practitioner ( London), Friday, June 14th.

Grindlay, D. (1985b). Aloe vera. The Garden, Journal of the Royal Horticultural Society, 110, 534-535.

Grindlay, D,, and Reynolds T. (1986). The Aloe vera phenomenon: A review of the properties and modern uses of the leaf Parenchyma gel. Journal of Ethnopharmacology,16, 117-151.

Abstract: This article has been said to be THE best overview of Aloe vera's properties and modern uses.

Gunther, R. T. (1934). The Greek Herbal of Dioscorides. Oxford University Press, Oxford.

Gupta, R. A., Singh, B. N., and Singh, R. N. (1981). Preliminary study on certain vedanasthapana (analgesic) drugs. Journal of Scientific Research in Plants and Medicines, 2, 110-112.

Gyanchandani, N. D., and Nigam, I. C. (1969, July). Anthraquinone drugs, II: Inadvertent acetylation of Aloe-emodin during preparation of aglycones from crude drugs: UV, IR, and NMR spectra of the products. Journal of Pharmaceutical Sciences,58(7), 833-835.

Abstract: Hydrolysis of anthraquinone glycosides with acetic acid leads to a partial acetylation of aloe-emodin, one of the liberated aglycones. With the aid of UV, IR, and NMR spectra, this hitherto unreported compound has been characterized as aloe-emodin monoacetate. The same compound is also formed when the simultaneous oxidation and hydrolysis of the glycosides is effected with FeCl 3 in presence of HCl and the resultant aglycones extracted with ethyl acetate.

Hagan, P. (2005, October 11). Plant juice ended my stomach agony: One tiny glass of Aloe vera a day could banish colitis symptoms. Good Health. The Daily Mail. London, England.

Abstract: A drink made from the Aloe vera plant is helping patients control the symptoms of ulcerative colitis, a disease that affects the bowels.

Halle, M. (2000, May 21). Health juice "danger" for mums-to-be. (News). Sunday Mirror London, England.

Abstract: Aloe vera is said to be highly effective at relieving such conditions as irritable bowel syndrome, colitis, ulcers and hiatus hernia. Article cautions women who are pregnant because of the possible aloin content in Aloe vera juice. [Note that Desert Harvest aloe vera products do not contain aloin or any of the other anthraquinones that cause problem during pregnancy.]

Halsell, G. (1975, November). Folk medicine: Ancestral gifts for modern ills. Prevention Magazine, 27, 83ff.

Hanley, D. C., Solomon, W. A. B., Saffran, B., and Davis, R. H. (PhD). (1982, June). The evaluation of natural substances in the treatment of adjuvant arthritis. Journal of the American Podiatry Association,72(6), 275-284.

Abstract: This work may provide effective treatment modalities for preventing and treating rheumatoid arthritis.

Hanno, P. M., Burks, D. A., Clemens, J. Q., Dmochowski, R. R., Erickson, D., FitzGerald, M. P., Forrest, J. B., Gordon, B., Gray, M., Mayer, R. D., Newman, D., Nyberg, Jr., L., Payne, C. K., Wesselmann, U., and Faraday, M. M. (2011, January).American Urological Association (AUA) Guideline: Diagnosis and Treatment of Interstitial Cystitis/Bladder Pain Syndrome.

Abstract: The purpose of this Guideline is to provide a clinical framework for the diagnosis and treatment of interstitial cystitis/bladder pain syndrome (IC/BPS).

Harding, T. B. C. (1979). Aloes of the world: A checklist, index and code. Excelsa,9, 57-94.

Harrison, R. K. (1961). Healing herbs of the Bible. Janus, 50, 16f.

Hart, L. A., van Enckevort, P. H., van Dijk, H., Zaat, R, de Silva, K. T .D., and Labadie, R. P. (1988). Two functionally and chemically distinct immunomodulatory compounds in the gel of Aloe vera. Journal of Ethnopharmacology, 23, 61-71.

Abstract: An aqueous extract of Aloe vera gel was analyzed guided by modulatory activity with regard to the in vitro activation of human complement and of human polymorphonuclear leucocytes (PMN).

Harwell, J. L. (1970). Plants used against cancer: A survey. Lloydia,33(1), 97.

Haydu, C., et al. (1997). Medical attributes of Aloe vera: The Aloe plant, Wilkes University, 1-8.

Hedendal, B. E. (DC, PhD). (N.D.). Super-Strength Aloe vera, almost a panacea: An overview of one of the most accepted, yet misunderstood, medicinal plans in history. Simply Natural Products.

Abstract: Discusses benefits of Aloe vera, especially cold processed.

Heggers, J. P. (PhD), Pineless, G. R. (BS), and Robson, M. C. (MD). (1979, September/October). Dermaide Aloe / Aloe vera gel: Comparison of the antimicrobial effects. Journal of American Medical Technologists,41(5), 293-294.

Abstract: This article from the University of Chicago Burn Center records a comparison between two Aloe vera products as to their comparative antimicrobial activity which is important in the treatment of burns and many other injuries. Aloe inhibits the growth of some of the most dangerous microbes.

Heggers, J. P., and Robson, M. C. (1983). Prostaglandins and thromboxanes. In Ninnemann, J. L. (Ed.), Traumatic Injury: Infection and Other Immunological Sequelae. University Park Press, Baltimore, 79-102.

Heinerman, J. (1982). Aloe vera, the divine healer. In Aloe Vera, Jojoba and Yucca. New Canaan, CT: Keats Publishing, Inc., 1-11.

Henderson, C. (1991, August 5). Substance boosts therapeutic effects of AZT. AIDS Weekly, 2-3.

Abstract: A complex carbohydrate compound purified from aloe vera appears to help drugs such as AZT and ACY block the pathology associated with HIV and herpes simplex virus. They also found that acemannan interfered with HIV's ability to reproduce in infected cells.

Henry, R. (1979, June). An updated review of Aloe vera. Cosmetics and Toiletries,94(6), 42-50.

Abstract: The purpose of this paper is to update what is happening with the aloe vera plant in respect to history, current findings of the medical industry, identification of some of the compounds, commercial applications of extracts, safety data, and efficacy of extracts in cosmetics.

Hirata, T., and Suga, T. (1977). Biologically active constituents of leaves and roots of Aloe arborescens var. natalensis. Zeitschrift Fur Naturforsch,32, 731-734.

Abstract: Several biologically active substances, such as aloenin, magnesium lactate, aloe-emodin, barbaloin, and succinic acid were found to be contained tin the leaf juice of Aloe arborescens Mill. Var. natalensis Berger, which has widely been used in domestic medicines. Aloenin and magnesium lactate were elucidated to exhibit an inhibitory action on the gastric juice secretion of rats and was taken to also be helpful for arthritis and rheumatic fever. Various constituents other than the above bioactive substances were found in the leaves and the roots of the plant.

Hirata, T., and Suga, T. (1978). Structure of aloenin, a new biologically-active bitter glucoside from Aloe arborescens var. natalensis. Bulletin of the Chemical Society of Japan,51(3), 842-849.

Abstract: Aloenin, a new bitter glucoside with an inhibitory activity for the gastric juice secretion of rats, was isolated from the leaves of Aloe arborescens Mill. var. natalensis.

Hirata, T., Sakano, S., and Suga, T.. (1981). Biotransformation of aloenin, a bitter glucoside constituent of Aloe arborescens, by rats. Experientia, 37, 1252-1253.

Abstract: Aloenin has been established to show an inhibitory activity for gastric juice.

Hodge, W. H. (1953). The drug Aloes of commerce, with special reference to the Cape species. Economic Botany,7, 99-129.

Hoffenberg, P. (1979). Aloe vera. Eine alte heilpflanze: Neu fiir die kosmetik. Seifen, Öle, Fette, Wachse,105, 499-502.

Horn, C. L. (1941). Botanical science helps to develop a new relief for human suffering. Journal of The New York Botanical Garden,42 (496), 88-92.

Abstract: Aloe is mentioned in relation to burns, diseases of the chest, wounds, ringworm, roundworm, as a purgative, X-ray burns, and other diseases.

Howe, M. (1996, July 1). Nature’s cure-all: Aloe vera. Country Living.

Abstract: Aloe vera appears to be an all-around herbal cure for many ailments. These range from burns, insect bites and rashes to medical applications as eye drops, toothpaste and anti-inflammatory agents. Although scientific proof of and research into all of Aloe’s claims remain in their early stages, evidence of Aloe vera’s healing qualities is mounting. A specific section is written concerning Leaky Gut Syndrome.

Hranisavljevic-Jakovljevic, M., and Miljkovic-Stojanovic, J. (1981). Structural study of an acidic polysaccharide isolated from Aloe arborescens Mill. I. Periodate oxidation and partial acid hydrolysis. Glasnik Hemiskog Druš'tva. Beograd.,46, 269-273.

Ikegami, S., et al. (1994). Viscous indigestible polysaccharides reduce accumulation of pentachlorobenzene in rats. Journal of Nutrition,124, 754-760.

Imanishi, K. (1993). Aloctin A, an active substance of Aloe arborescens Miller as immunomodulator. Department of Microbiology and Immunology, Tokyo Women’s Medical College, Tokyo, Japan, 1-4.

Abstract: In this article, I would like to describe the antitumor activity of Aloe A using methylcholanthrene-induced nurine fibrosarcoma (MethA) and lymphocytic leukemia in syngeneic mouse systems.

Imanishi, K., Ishiguro, T., Saito, H., and Suzuki, I. (1981). Pharmacological studies on a plant lectin Aloctin A. I. Growth inhibition of mouse methylcholanthrene-induced fibrosarcoma (Meth A) in ascites form by Aloctin A. Experientia,37, 1186-1187.

International Aloe Science Council, Inc. (N.D.). Aloe vera analysis: High pressure liquid chromatography bonded amine assay. Austin, TX: IASC.

Abstract: Reagents, instrument conditions, procedure, standard reference sample, location of "E" peak in products, reference HPLC scans.

Ito, S., Teradaira, R., Beppu, H., Obata, M., Fujita, K., and Nagatsu, T. (N.D.). Biochemical properties of carboxypeptidase in Aloe arborescens Miller var. natalensis Berger. 77-86.

Abstract: A carboxypeptidase was partially purified from Aloe arborescens Miller var. Natalensis Berger in a scale suitable for pharmacological studies. The results indicate that aloe enzyme is a serine carboxypeptidase and appears to contain a sulfydryl group that may be involved in its inactivation.

Ivy Research. (1978, October-December). Wound Healing Assay, Ivy Research Protocol #3791.

Abstract: To determine whether the materials tested interfere or enhance the healing process of superficial dermal wounds.

Jain, K. K. (1973). The Amazing Story of Health Care in New China. Emmaus, Pennsylvania, 128f.

Jelly Feng, Shanghai Office. (2002, September 5). Aloe vera a favoured natural ingredient in Shanghai life.

Abstract: Studies suggest that, in addition to its cosmetic properties, Aloe Vera can also be used in fighting cancer, bacteria and inflammation, reducing blood sugar and blood fat levels and healing wounds. No wonder the plant is so widely used in skin care, cosmetic, medical, healthcare and food products, and that Aloe products are popular in the market.

Jia, Qi (Dr.). Research focuses on chromones in Aloe. Univera Pharmaceuticals, Inc.

Abstract: Dr. Qi Jia of Univera Pharmaceuticals investigates the role chromones may play in the anti-inflammatory effects Aloe displays. [LINK TO IASC]

Jones, K.. (2006). Dietary aloe vera supplementation and glycemic control in diabetes. Nutraceuticals.

Abstract: A growing body of preclinical and clinical research shows that the gel of the Aloe vera plant, administered as a juice or in dried form, has significant antidiabetic activity. Not surprisingly, studies using animal models outnumber clinical trials, but animal studies provide supporting evidence and often provide insights into mechanisms of action.

Jones, K. (2008, February 26). Quenching free radicals with aloe vera. Inside cosmeceuticals,

Abstract: Over the past two decades, skin care has advanced at a rate rivaling that of technology. Just as it used be enough for cell phones to simply make phone calls, it used to be enough for skin care products to simply cleanse, tone and moisturize. Those days are long gone. As baby boomers started showing the first signs of aging, they demanded more of their skin care products. They insisted on multi-tasking formulas that could reduce fine lines and wrinkles, firm sagging skin and make dull complexions lustrous again.

Kahlon, J., et al. (1991). Inhibition of AIDS virus replication by Acemannan in vitro. Molecular Biotherapy, 3, 127-135.

Kameyama, S., and Shinho, M. (1980). Wound-healing compositions from Aloe arborescens extracts. Japanese patent 79,151,113. Chemical Abstracts,93, 10375y.

Karaca, K., Sharma, J. M., and Nordgren, R. (1995). Nitric oxide production by chicken macrophages activated by Acemannan. International 1. Immuno Pharmacology, 17(3), 183-188.

Abstract: Cultures of normal chicken spleen cells and HD11 line cells produce nitric oxide (NO) in response to Acemannan, a complex carbohydrate derived from the Aloe vera plant. Neither cell type produced detectable amounts of NO in response to similar concentrations of yeast mannan, another complex carbohydrate. Nitric oxide production was dose dependent and inhibitable by the nitric oxide synthase inhibitor N G-methyl-L-arginine. In addition, the production of NO was inhibited by preincubation of ACM with concanavalin A in a dose-dependent manner. These results suggest that ACM-induced NO synthesis may be mediated through macrophage mannose receptors, and macrophage activation may be accountable for some of the immunomodulatory effects of ACM in chickens.

Kassab, S., Cummings, M., Berkovitz, S., van Haselen, R., and Fisher P. (2009, Apr). Homeopathic medicines for adverse effects of cancer treatments. Cochrane Database Syst Rev. 2009 Apr 15;(2):CD004845. doi: 10.1002/14651858.CD004845.pub2. Comment in Otolaryngol Head Neck Surg. 141(2), 162-165.

Abstract: Homeopathic medicines are used by patients with cancer, often alongside conventional treatment. Cancer treatments can cause considerable morbidity and one of the reasons patients use homeopathic medicines is to help with adverse effects. OBJECTIVES: Evaluate effectiveness and safety of homeopathic medicines used to prevent or treat adverse effects of cancer treatments. CONCLUSIONS: This review found preliminary data in support of the efficacy of topical calendula for prophylaxis of acute dermatitis during radiotherapy and Traumeel S mouthwash in the treatment of chemotherapy-induced stomatitis. These trials need replicating. There is no convincing evidence for the efficacy of homeopathic medicines for other adverse effects of cancer treatments. Further research is required.

Kavalier, F. (N.D.). A question of health: I can't seem to get rid of the infection that is giving me a terrible cough. And how can I produce my own aloe vera juice at home? (Features) (Bug that won't go away). The Independent London, England.

Abstract: Answers these questions.

Kawai, K., Beppu, H., Koike, T., Fujita, K., and Marunouchi, T. (N.D.). Tissue culture of Aloe arborescens Miller var. natalensis Berger. 141-154. .

Abstract: We examined the culture conditions for callus induction in the tissues of Aloe arborescens.

Kelly, G. (1999). Larch arabinoglactan: Clinical relevance of a novel immune-enhancing polysaccharide. Altem Medical Review, 4(2), 96-103.

Khan, R. H. (1983). Investigating the amino acid content of the exudate from the leaves of Aloe barbadensis (Aloe vera). Erde International, 1, 19-25.

Khaing, T.A. (2011). Evaluation of the antifungal and antioxidant activities of the leaf extract of Aloe vera (Aloe barbbadenisis Miller). World Academy of Science: Engineering and Technology,75.

Abstract: Aloe vera has been used worldwide both for pharmaceutical, food, and cosmetic industries due to the plethora of biological activities of some of its metabolites. The aim of this study was to evaluate the antifungal and antioxidant activities of the leaf extract. The antifungal activity was determined by the agar-well diffusion method against plant and human fungal pathogens. The methanol and ethanol portions of the extracts studies were more bioactive than ethyl acetate portion. It was also observed that the activity was more pronounced on plant pathogen than human pathogen except Candida albicans. This is an indication that the extract has the potential to treat plant fungal infections. The Aloe extract showed the significant antioxidant activity by the DPPH radical scavenging method. Therefore, the Aloe extract provided as natural antioxidant has been used in health foods for medical and preservative purposes.

Kislyak, N., and Posnyak, I. (N.D.). Hypochromic anemia in small children treated with syrup of Aloe with iron. Extract of Aloe, Supplement to Clinical Data, Medexport, USSR, Moscow.

Abstract: In addition to the fact that aloe itself is a good biogenic stimulator, it preserves the iron in its most active form, reduces the irritation effect of iron on the mucosa of the gastrointestinal tract, and imparts a pleasant taste to the preparation. There are indications that the new preparation is highly effective in the treatment of hypochromic anemias in adults as well.

Klein, L. (1993, March 1). Aloe vera: Au naturel. Vibrant Life.

Abstract: Use of aloe vera as a plant and includes some discussion on specific properties of the plant.

Koenig, M. C. (1977, October). Is topical Aloe vera plant mucus helpful in burn treatment? Journal of the American Medical Association, 238, 1170.

Koshioka, M., Koshioka, M., Takino, Y., and Suzuki, M. (1982). Studies on the evaluation of Aloe arborescens Mill. var. natalensis Berger and Aloe extract. International Journal of Crude Drug Research, 20, 53-59.

Kozak, S. A., Stepanova, O. S., Checkurda, A. I., Prudnik, N. Z., and Chikalo, I. I. (1971). Mineral composition of aloe leaves and aloe extracts. Fiziol. Akitiv. Veshchestva. Res-pub. Meghvedom, 5b(3), 302 (Chem. Abs. 77:58741y).


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