Bibliography

Kupchan, S. Morris, & Karim, Aziz. (N.D.). Tumor inhibitors, Aloe emodin Antileukemic principle isolated from rhamnus frangula L. Lloydia, 39.

Abstract: This breakthrough research report identifies the ingredient that gives Aloe its anti-tumor characteristic on the cellular level.

Kurilenko, H. A. (1974). Use of Aloe in complex treatment of patients with focal pulmonary T.B. Vrach Delo, 10, 110-111.

Kurilenko, M. I. (N.D.) On studying the ampoullated Aloe extract. In Aloe Vera: New Scientific Discoveries by Max Skousen, 98-101.

Abstract: The aloe extracts prepared from fresh and dried raw stock are found to be identical as to the total amount of acids and cations, the pH, and also to chromatographic behavior on paper.

Kuzuya, H. (2006, January 1). Inhibitory effects of Aloe carboxypeptidase fraction on streptozotocin-induced enhancement of vascular permeability in the pancreatic islets. Phytomedicine: International Journal of Phytotherapy & Phytopharmacology.

Abstract: The protective actions of components isolated from Aloe arborescens Miller var. natalensis Berger on streptozotocin-induced necrosis of B cells in the pancreatic islets of the mouse were investigated to clarify its action mechanism involved in anti-diabetic effects.

Kyker, Kimberly D., Coffman, Jean, & Hurst, Robert E. (2005, March 23). Exogenous glycosaminoglycans coat damaged bladder surfaces in experimentally damaged mouse bladder. BMC Urology, 5, 4.

Abstract: Interstitial cystitis is often treated with exogenous glycosaminoglycans such as heparin, chondroitin sulphate (Uracyst), hyaluronate (Cystistat) or the semi-synthetic pentosan polysulphate (Elmiron). The mechanism of action is presumed to be due to a coating of the bladder surface to replace the normally present chondroitin sulphate and heparin sulphate lost as a result of the disease. This study used fluorescent labeled chondroitin sulphate to track the distribution of glycosaminoglycans administered intravesically to mouse bladder that had been damaged on the surface. Glycosaminoglycan administered intravesically does bind to damaged bladder. Given that the changes seen following bladder damage resemble those seen naturally in interstitial cystitis, the mechanisms proposed for the action of these agents is consistent with the coating of damaged bladder.

Lakeland Laboratories/Hazleton Laboratories, Incorporated. (1968, May 14). Acute oral administration - Rats, Acute Oral Dose Range - Dogs, Acute Dermal Application - Rabbits, Projects Nos. 534-100, 534-101, and 534-102.

Lakeland Laboratories/Hazleton Laboratories, Inc. (1969, January 31). 13-week repeated dermal application - Rabbits, Project No. 534-103.

Langstone, Anthony. (2000, February 19). Bitter truth: Aloe vera. The Epoch Times.

Abstract: Aloe vera is once again gaining the interest of researchers. Aloe means bitter in Arabic, and vera is Latin for truth.

Leun, Albert Y. (PhD). (1977, June). Effective ingredients of Aloe vera. Drugs and Cosmetics, 34-35, 154-155.

Abstract: Effective ingredients of Aloe vera.

Leun, Albert Y. (1985, September). Aloe vera update: A new form questions integrity of old. Drug & Cosmetics Industry, 42-46.

Abstract: Discusses the ability to now stabilize processed yet active Aloe so that more reliable tests may be done.

Leun, Albert Y. (1977). Aloe vera in cosmetics. Drugs & Cosmetic Industry,120, 34-35, 154-l55.

Leun, Albert Y. (1978). Aloe vera in cosmetics. Excelsa,8, 65-68.

Levene, T. (1983, July 24). Medicine men hit town with cactus cure. Sunday Times ( London).

Levenson, S., & Somova, K. (N.D.). Periodontosis (disease of the bone holding teeth) treated with Aloe extract. Irkutak Medical Institute, Russia.

Abstract: Treatment of periodontosis with aloes extract produced positive results, both direct and remote.

Li-Shih-Chen. (1973). Chinese Medicinal Herbs, translated by F. P. Smith and G. A. Stuart, San Francisco, 29f.

Link, J. A. (1978, December). Burns healed fast. Prevention Magazine, 30, 17f.

Lion Corp. (1981). Cosmetics for skin. Japanese patent 80,104,205. Chemical Abstracts,94, 20244b.

Lorenzetti, Lorna J., Salisbury, Rupert, Beal, Jack L., & Baldwin, Jack N. (1964, October). Bacteriostatic property of Aloe vera. Journal of Pharmaceutical Science,53(10), 1287.

Abstract: Antibacterial property of Aloe vera. Freeze-dried juice obtained from Aloe vera and heated for 15 minutes at 80° inhibited several test microorganisms.

Lovelady, Sara. (2004, October 1). Diabetes: The all-American disease: Given the rise in diabetes, nutraceutical solutions are in demand. Nutraceuticals World.

Abstract: A placebo-controlled, single-blind human clinical trial found that diabetics receiving 15 milliliters of Aloe gel twice a day for 42 days experienced 43 % and 44% reductions in blood sugar and blood triglycerides, respectively, while controls experienced no change.

Loveman, Adolph B. (MD). (1937). Leaf of Aloe vera in treatment of Roentgen ray ulcers: Report of 2 additional cases, Archives of Dermatology and Syphilology,36, 838-843.

Abstract: Reports two cases of aloe used for roentgen burns.

Lowenthal, L. J. A. (1949). Species of Aloe (other than Aloe vera) in the treatment of Roentgen dermatitis. The Journal of Investigative Dermatology,12, 295-298.

Lushbaugh, C. C. (MD), & Hale, D. B. (Dr., BS). (1953, July). Experimental acute radiodermatitis following beta irradiation. V. histopathological study of the mode of action of therapy with Aloe vera. Cancer,6, 690-698.

Abstract: Animal research on acute radiation damage.

Lutomski, J. (1984). Aloe, topfzierpflanze mit therapeutischer wirkung. Pharmazie in unserer Zeit,13, 172-176.

Mackee, G. M. (1938). X-rays and Radium in the Treatment of Diseases of the Skin, 3 rd ed. Lea and Febiger, Philadelphia, 319-320.

Madis Laboratories. (1983). Aloe vera L. and its products, applications and nomenclature. Cosmetics and Toiletries,98, 99-104.

Madis Laboratories. (1984). Aloe vera gel. The ageless Beauty Ingredient, 9th ed. South Hackensack, NJ: Dr. Madis Laboratories Inc.

Madis Laboratories, Inc. (N.D.). Veragel: Purified Aloe leaf extract derived from Aloe vera gel.

Abstract: History of aloe gel as well as its applications and uses.

Makino, Kenji, Yagi, Akira, & Itsuo Nishioka. (1974). Studies on the constituents of Aloe arborescens Mill. var. natalensis Berger. II. The structures of two new aloesin esters. Chem. Pharm. Bulletin, 22(7), 1565-1570.

Abstract: Two new aloesin esters were isolated from the fresh leaves of Aloe arborescens Mill. var. natalensis Berger. These esters are the first naturally occurring 2"-O-acylated C-glucosyl compounds.

Malhotra, Rajneesh, Wormald, Mark R., Rudd, Pauline M., Fischer, Per B., Dwek, Raymond A., & Sim, Robert B. (1995, March). Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via mannose-binding protein. Nature Medicine, 1(3), 237-243.

Makino, Kenji, Yagi, Akira, & Itsuo Nishioka. (1974). Studies on the constituents of Aloe arborescens Mill. var. natalensis Berger. II. The structures of two new aloesin esters. Chem. Pharm. Bulletin, 22(7), 1565-1570.

Mandal, G., & Das, A. (1980a). Structure of the d-galactan isolated from Aloe barbadensis Miller. Carbohydrate Research,86, 247-257.

Mandal, G., & Das, A. (1980b). Structure of the glucomannan isolated from the leaves of Aloe barbadensis Miller. Carbohydrate Research,87, 249-256.

Mandal, G., Ghosh, R., & Das, A. (1983). Characterisation of polysaccharides of Aloe barbadensis Miller: Part III—Structure of an acidic oligosaccharide. Indian Journal of Chemistry, 22B, 890-893.

Mandeville, Frederick B. (MD). (1939). Aloe vera in the treatment of radiation ulcers of mucous membranes. Radiology, 32, 598-599.

Abstract: Literature on Aloe vera therapy for radiation ulcers of the skin is briefly reviewed. Radiation ulcers of the mucous membranes and adjacent tissues of body cavities may also be treated with the fresh leaf of Aloe vera. A case of osteo-radio-necrosis of the mouth so treated and well two years following healing is briefly reported.

Mangelson, Mark L. (DDS), Carson, Robert E., Uydea, Gregg T., Moore, Timothy E., & Cucchiara, Andrew J. (N.D.). Effects of Aloe vera irrigation on pathogenic microorganisms associated with moderate to advanced adult periodontitis. University of Oklahoma College of Dentistry, Graduate Periodontics Program.

Abstract: Controlled in vivo human study of the effects of Aloe vera on pathogenic microorganisms associated with adult periodontitis.

Mapp, R. K., & McCarthy, T. J. (1970). The assessment of purgative principles in Aloes. Planta Medica,18, 361-365.

Mary, Nouri Y., Christensen, Bernard V., & Beal, Jack L. (1956, April). A paper chromatographic study of Aloe, aloin and of cascara sagrada. Journal of the American Pharmaceutical Association, XLV(4), 229-232.

Abstract: A qualitative and quantitative study of aloe, aloin, and cascara sagrada by the use of paper chromatography was undertaken. The results indicated the presence of aloe-emodin and anthranol in the free state and in glycosidal combination in all five of the drugs investigated. In addition, the Curacao aloe contained chrysophanic acid and the cascara sagrada contained chrysophanic acid and emodin in their free state and also in glycosidal combination.

McCarthy, T. J. (1968). The metabolism of anthracene derivatives and organic acids in selected Aloe species. Planta Medica, 16, 348-356.

McCarthy, T. J. (1969, February). Distribution of glycosyl compounds in South African Aloe species. Planta Medica,17(1), 1-7.

Abstract: In the slightly more than one hundred Aloe species examined, it has been found that the C-glycosyl anthraquinones aloin and homonataloin appear in nearly half these species, and in roughly equal proportions. The C-glycosyl benzopyrone derivative, aloesin, appears in more than one quarter of the total species and almost exclusively in the species containing aloin or homonataloin. The O-glycosyl compounds of aloin (aloinosides) and of chrysophanol appear far less commonly.

McCarthy, T. J. (1971). Aloe research. Aloe,9, 20-23.

McCarthy, T. J., & Mapp, R. K. (1970, January). A comparative investigation of methods used to estimate aloin and related compounds in Aloes. Planta Medica,18(1), 36-43.

Abstract: The assay of aloin in aloes are investigated using different methods, and these are discussed. Furthermore, the presence of homonataloin, aloinosides and similar compounds in aloes are investigated in relation to these assay methods. The effect of heating aloe juice in relation to aloin destruction is also discussed.

McCarthy, T. J., & van Rheede van Oudtshorn, M. C. B. (1966). The seasonal variation of aloin in leaf juice from Aloe ferox and Aloe marlothii. Planta Medica,14, 62-65.

McDaniel, H. Reginald (MD), Carpenter, Robert H. (DVM), Kemp, Maurice C. (PhD), Kahlon, Jasbir (Dr., PH), & McAnalley, Bill H. (PhD). (1989). A favorable response of HIV-1-infected patients to oral acemannan and development of prognostic criteria for clinical responsiveness.

Abstract: Reports two studies. The objective of the first was to assess response of HIV-1 patients to acemannan therapy; the objective of the second was to determine if a response to acemannan treatment could be predicted based on certain pre-therapy laboratory values. Three patients predicted to improve in all three criteria failed to do so, although they did improve in two parameters. None predicted to respond favorably failed to show some improvement. Three patients predicted to show no improvement did improve in at least one category with two of the patients improving in all three.

McDaniel, H. Reginald (MD), McAnalley, B. H. (PhD), & Carpenter, R. H. (DVM). (N.D.). The basic science and principles for the use of acemannan in clinical medicine. Grand Prairie, TX: Fisher Institute for Medical Research at Dallas-Fort Worth Medical Center.

Abstract: Acemannan in clinical medicine.

McKeown, Edward C. (1983, June). Aloe vera: The quest for the “curative” missing link. Drug & Cosmetic Industry, 30ff.

Abstract: This article reviews what we currently know (or do not know) about the composition and analysis of aloe and examines the quest for the "curative" ingredient missing link.

Meadows, Tim P. (1980, November). Aloe as a humectant in new skin preparations. Cosmetics & Toiletries, 95, 51-56.

Abstract: Article presents a few of the types of products in which aloe gel may be used. Aloe gel may be used in any system in which moisturization or mildness is wanted. Alone or in conjunction with other materials for that purpose.

Mebe, Paul P. (1987). 2´-p-Methoxycoumaroylaloeresin, A c-glucoside from Aloe excelsa. Phytochemistry, 26(9), 2646-2647.

Abstract: I report here a chemical investigation of the dried leaf surfaces of Aloe excelsa which resulted in the isolation of a new natural compound, p-methoxycoumaroylaloeresin (2) and known compounds, aloesin (1) [5], homonataloin [6], aloin [4] and 1,5 dihydroxy-e-hydroxymehtylanthraquinone [7] from the acetone extract.

Miller, Alan L. (2003, November 1). Nutritional support for wound healing. Alternative Medicine Review.

Abstract: Discusses wound healing with nutritionals including Aloe vera. Includes a large list of references.

 

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