Dosage Recommendations for IC Patients
Interstitial cystitis patients in the first double-blind, placebo-controlled clinical trial took 6 Desert Harvest freeze-dried, super-strength aloe vera capsules per day for three months, 3 capsules in the morning and 3 in the evening (about 12 hours apart) with a full 8-ounce glass of liquid. It does not matter whether you take the aloe vera with food or without. It works the same either way. However, it is important to drink 8 ounces of liquid with each dose. Avoid taking the evening dose at bedtime, or the liquid you drink will cause more frequent trips to the bathroom in the night. Based on our anecdotal findings with more than 50,000 IC/PBS patients, we plan to conduct a dosing study to determine which dose works the best. In the meantime, here are our latest recommendations:
First Month : 6 capsules per day (3 in the morning and 3 in the evening). If you are symptom free after the first 30 days, continue taking 6 capsules a day for the next 2 months. However, if you still have some symptoms after the first 30 days, then:
Second Month : 9 capsules per day (3 in the morning, 3 in the afternoon, and 3 in the evening). If you are symptom free after 60 days, continue taking 9 capsules a day for the third month. However, if you still have some symptoms, then:
Third Month : 12 capsules per day (4 in the morning, 4 in the afternoon, and 4 in the evening). If the symptoms do not respond within 3 months while following the 6/9/12 dosage recommendations, we assume that you are one of the 12.5% of patients who will not respond to the aloe vera at all. In our database of more than 8,000 IC/PBS patients, 75% received at least some relief and 42% had total symptom control, although symptoms can return if the aloe vera is discontinued.
Maintenance Dose: After three months, the daily dose can be decreased by one capsule per week until symptoms return (for instance, week one: take 5 capsules per day, week two: take 4 capsules per day, week three: take 3 capsules per day). When you notice symptoms, increase the daily dose by one capsule and continue on this maintenance dose. On bad days, a burst of 3 to 6 extra capsules at any time of day may bring symptoms back under control for many IC/PBS patients. It is safe to take 21 capsules or more per day.
Flare-ups: We recommend 6 capsules every 4 hours until you have your symptoms back under control. Most people only have to take the first 6 capsules.
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