Bibliography By Topic

BURNS & RADIATION (see also Dermatologic Uses, and Wound Healing)

Cera, Lee M. (DVM), Heggers, John P. (PhD), Robson, Martin C. (MD), & Hafstrom, William J. (MD). (1980, September/October). The therapeutic efficacy of Aloe vera cream in thermal injuries: Two case reports. Journal of the American Animal Hospital Association,16, 768-772.

Abstract: This report by the University of Chicago Burn Center is about two dogs, both mixed shepherds, who were accidentally burned over such a large portion of their bodies that ordinary treatment would have been considered nearly futile. The very successful use of an Aloe vera cream is carefully documented.

Cera, Lee M. (DVM), Heggers, John P. (PhD, MT[AMT]), Hafstrom, William J. (MD), & Robson, Martin C. (MD). (1982, July/August). Therapeutic protocol for thermally injured animals and its successful use in an extensively burned Rhesus monkey. Journal of the American Animal Hospital Association,18, 633-638.

Abstract: This article from the University of Chicago Burn Center, is exceptional because the 70% burns received accidentally by this monkey should have been fatal, but the animal was not only saved but quickly returned to good health by treatment, the primary part of which was by Aloe vera.

Crewe , J. E. (MD). (1939, January 6). Aloes in the treatment of burns and scalds. Minnesota Medicine,22, 538-539.

Abstract: This method has proved so simple and the results have been so satisfactory, that I have not used any other treatment for burns since the spring of 1935. I employ an ointment of which the active ingredient is Aloe.

Collins, C. E. (DDS, MD), & Collins, Creston (MS). (1935, March). Roentgen dermatitis treated with fresh whole leaf of Aloe vera. American Journal of Roentgenology, 33(3), 396-397.

Abstract: Fresh Aloe vera used for x-ray dermatitis. This article by Dr. Creston Collins and his father was the landmark report, creating waves of interest throughout the world among medical science. Since the new wonder treatment of roentgen rays had some tragic side effects, the ancient and often scoffed at “Medicine Plant” provided the only workable solution for many cases.

Cope, Oliver. (1948) .The burn problem. Advances in Military Medicine,1, Chapter XII, 149-154.

Abstract: Pearl Harbor, World War II, and other burn disasters prompted this discussion of possible burn treatments.

Farkas, Alexander (Dr.). (1963). Topical medicament including polyuronide derived from Aloe. Chemical Abstracts, 60, 378g-379a. Patent on one of the active ingredients of Aloe vera, U.S. Patent No. 3,103,466, received on September 10, 1963. Claim was filed on December 23, 1954.

Abstract: The product, while quickly relieving pain, particularly from burns, appears thereby to have an analgesic and anesthetic effect; particularly in the type of healing rapidly promoted by the composition, it appears to have a detoxifying effect that may be the results of the reducing action inherent in the polyuronide without causing irritation, because burns, even second and third degree burns, become healed unusually rapidly, and the skin re-forms with rapid granulating, without scab formation.

Loveman, Adolph B. (MD). (1937). Leaf of Aloe vera in treatment of Roentgen ray ulcers: Report of 2 additional cases, Archives of Dermatology and Syphilology,36, 838-843.

Abstract: Reports two cases of aloe used for roentgen burns.

Lushbaugh, C. C. (MD), & Hale, D. B. (Dr., BS). (1953, July). Experimental acute radiodermatitis following beta irradiation. V. histopathological study of the mode of action of therapy with Aloe vera. Cancer,6, 690-698.

Abstract: Animal research on acute radiation damage.

Mandeville, F. B. (1939). Aloe vera in treatment of radiation ulcers of mucous membranes. Radiology, 32, 598-599.

Abstract: Literature on Aloe vera therapy for radiation ulcers of the skin is briefly reviewed. Radiation ulcers of the mucous membranes and adjacent tissues of body cavities may also be treated with the fresh leaf of Aloe vera. A case of osteo-radio-necrosis of the mouth so treated and well two years following healing is briefly reported.

Obata, Masafumi, Ito, Shosuke, Beppu, Hidehiko, Fujita, Keisuka, & Nagatsu, Toshiharu. (N.D.). Mechanism of anti-inflammatory and anti-thermal burn action of Aloe arborescens Mill. var. natalensis Berger. Fujita Health University, Japan, 19-28.

Abstract: Carboxypeptidase (Cpase) was partially purified from Kidachi aloe (Aloe Arborescens Mill. var natalensis Berger) by FPLC system, and was administered intravenously to female ICR mice with inflammation. The enzyme preparation revealed significant effects on alleviation of pain and inhibition of vascular permeability in abdominal region. It also revealed an anti-thermal burn action on rat’s hind paws, when it was administered to female Wister rat intravenously.

Rovatti, B., & Brennan, R. J. (1959). Experimental thermal burns. Industrial Medicine and Surgery,28, 364-368.

Abstract: A comparative study of the immediate and delayed histopathological changes of the skin in untreated and treated thermal burns.

Rowe, Tom D., Lovell, B. K., & Parks, Lloyd M. (1941). Further observations on the use of Aloe vera leaf in the treatment of third-degree X-ray reactions. Journal of the American Pharmaceutical Association,30, 266-269.

Abstract: This present report deals with further observations on the use of the fresh jell, or pulp, of the leaf, as well as other portions of the leaf, in the treatment of experimentally produced third degree X-ray reactions on the skin of white rats.

Rowe, Tom D. (1940). Effect of fresh Aloe vera gel in the treatment of third-degree roentgen reactions on white rats. Journal of the American Pharmaceutical Association,29, 348-350.

Abstract: From the results obtained, fresh Aloe vera jell shows some promise of being of value in the treatment of X-ray reactions.

Rowe, Tom D., & Parks, Lloyd M. (1941). A phytochemical study of Aloe vera leaf. Journal of the American Pharmaceutical Association,30, 262-266.

Abstract: The study reported in this paper was undertaken in connection with an attempt to isolate and characterize the principle contained in Aloe vera leaf that is responsible for its activity in promoting the healing of third degree x-ray reactions on white rats.

Ship, Arthur George (MD), & Einstein, Albert. (1977, October 17). Is topical Aloe vera plant mucus helpful in burn treatment? Journal of the American Medical Association,238(16), 1770.

Abstract: This article is not a clinical study. It acknowledges that application of Aloe vera to a burn provides immediate pain relief and speeds the healing process, with no infection or systemic symptoms resulting, and answers what the ingredients of this plant are that give these results.

Smoot, E. Clyde (MD). (1981, March 14-17). The effects of anti-inflammatory agents on acute and late radiation skin changes in the rat. 27 th Annual Meeting Report, Plastic Surgery Research Council, San Diego, California.

Abstract: This article by the University of Chicago Burn Center deals with one of the earliest recognized benefits of Aloe vera. Back in the thirties, when x-Ray treatments were first being used, medical reports showed that Aloe vera was the only thing that would heal many of the radiation induced lesions of the skin. Now, with this testing on rats, the data is established in true, scientific testing.

Strickland, Faith M., Pelley, Ronald P., & Kripke, Margaret L. (1994, February). Prevention of ultraviolet radiation-induced suppression of contact and delayed hypersensitivity by Aloe barbadensis gel extract. The Journal of Investigative Dermatology, 102(2), 197-204.

Abstract: These studies demonstrate that topical application of Aloe barbadensis gel extract to the skin of UV-irradiated mice ameliorates UV-induced immune suppression by a mechanism that does not involve DNA damage or repair.

Wright, Carroll S. (MD). (1936). Aloe vera in the treatment of Roentgen ulcers and telangiectasis. Journal of the American Medical Association,106(16), 1363-1364.

Abstract: From the case reported, it would seem that x-ray ulceration, even of several years' duration, will respond to the use of aloe vera. The permanence of results can be determined only by watching cases thus treated over a period of time. Little can be expected in the treatment of telangiectasis as a result of irradiation beyond a smoothing and softening of the affected skin.

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