Glucosamine Chondroitin Sulfate & Quercetin synergistically help to inhibit mast cell activation, promote bladder health and support the protective layer of the bladder.
Mast cells have been found to be raised in patients suffering from IC. As a result, IC bladders also contain about double the histamine as a healthy bladder. Histamine plays a role in inflammation.
Although mast cells are usually present in the lamina propria (the connective tissue just under the urothelium) of healthy bladders, they are found in increased numbers in the submucosal layer of the bladder wall and especially in the muscle layer (detrusor muscle) surrounding the bladder in interstitial cystitis sufferers.
When mast cells are activated, they generally present as an allergic/inflammatory condition that can affect different body symptoms and express as IBS, depression, skin conditions and interstitial cystitis. Mast cells release inflammatory compounds such as histamine, that cause swelling, burning and pain.
The prevalence of allergies in IC patients has been reported to be 40 – 80% and the condition often co-exists with autoimmune conditions. Some people report that their IC flares up more in allergy season. This may be because mast cells are more frequently triggered. Interstitial cystitis has some common features with allergies such as increased mast cells, histamine and inflammation.
Quercetin (90 Capsules) is a natural antihistamine, anti-inflammatory and contains antioxidant flavonoids found in fruits & vegetables that support collagen development, balanced immune response and cardiovascular protection. Flavonoids support capillary wall stability and healthy collagen development, balance immune response, and provide cardiovascular protection by reducing the oxidation of LDL cholesterol. Mast cells have been found to be raised in patients suffering from IC. As a result, IC bladders also contain about double as much histamine as a healthy bladder. Histamine plays a role in inflammation. Quercetin has been shown to inhibit the release of histamines and other immune mediators, so it is widely used by allergy sufferers. Antihistamine medications are often prescribed by doctors to treat IC/BPS and nonbacterial prostatitis.
Glucosamine Chondroitin (120 capsules) Studies have shown that the combination of glucosamine and chondroitin provide the building blocks for the development of healthy cartilage and connective tissue and may provide the same anti-inflammatory action as ibuprofen with associated relief for Crohn’s disease, ulcerative colitis (UC), and irritable bowel syndrome (IBS). The GAG layer of the bladder is primarily made up of glycosaminoglycans like chondroitin and glucosamine. It is theorized that the GAG layer of the bladder is “leaky” in people with IC/PBS and nonbacterial prostatitis. If that is the case, then supplementing your diet with glucosamine and chondroitin might replace the lost protective molecules in your bladder. Several food supplements containing these nutrients have been studied in IC/PBS patients with positive results. Desert Harvest Glucosamine/Chondroitin is IC-friendly and shellfish-free.
Read more about the Allergic Bladder
10% OFF when you buy 4 to 11 Desert Harvest products
15% OFF when you buy 12 or more Desert Harvest products
* excludes Aloe Vera 180 capsules