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Chemical Constituents and Nutrients - Bibliography by Topic

Bogaard, M. P. (1985, July). Report on the analysis of Aloe vera gel. (Report prepared on behalf of Unisearch Limited for Friendship Aloe Vera Pty. Ltd. Brookvale).

Abstract: Gives a tables that lists the results of the total solids determination and the elemental analyses. Originals of the infra-red spectra are included with the report.

Bouchey, G. D., and Gjerstad, G. (1969). Chemical studies of Aloe vera juice II: Inorganic ingredients. Quarterly Journal of Crude Drug Research, 9(4), 1445-1453.

Abstract: An investigation of the mineral constituents of Aloe vera.

Choi, S., and Chung, M. (2003, March). A review on the relationship between Aloe vera components and their biologic effects. Seminars in Integrative Medicine, 1(1), 53-62.

Abstract: Aloe vera (Aloe barbadensis Miller) is a perennial succulent belonging to the Liliaceal family, and is called the healing plant or the silent healer. As a result of its use as folk medicine, it is claimed that aloe vera has wound and burn healing properties, and anti-inflammatory, and immunomodulatory effects. Aloe vera is used in a variety of commercial products because of these therapeutic properties. It is being used as a whole extract, however, and the relationship between the components of the extract and its overall effect has not been clarified. A more precise understanding of the biologic activities of these is required to develop aloe vera as a pharmaceutical source. Many attempts have been made to isolate single, biologically active components, to examine their effects, and clarify their functional mechanism. This review focuses on the relationship between the isolated aloe vera components (ie, glycoproteins, anthraquinones, saccharides, low-molecular-weight substances) and their presumed pharmacologic activities.

Davis, Robert H. (1992, Autumn). Comments on the Aloe leaf. Aloe Today.

Abstract: General comments about Aloe including the structure of the leaf, how Aloe vera is made, skin penetration by mucilage and aloe vera, the aloe leaf assay, and the aloe vera cell.

Gjerstad, G. (1971). Chemical studies of Aloe vera juice I: Amino acid analysis. Advancing Frontiers of Plant Sciences, 28, 311-315, (Biol. Abs. 54:33019).

Abstract: The objective of this study was to ascertain the chemical composition of this alleged wonder drug.

Henry, R. (1979, June). An updated review of Aloe vera. Cosmetics & Toiletries, 94:6, 42-50.

Abstract: The purpose of this paper is to update what is happening with the aloe vera plant in respect to history, current findings of the medical industry, identification of some of the compounds, commercial applications of extracts, safety data, and efficacy of extracts in cosmetics.

Hirata, T., and Suga, T. (1977). Biologically active constituents of leaves and roots of Aloe arborescens var. natalensis. Zeitschrift Fur Naturforsch, 32, 731-734.

Abstract: Several biologically active substances, such as aloenin, magnesium lactate, aloe-emodin, barbaloin, and succinic acid were found to be contained tin the leaf juice of Aloe arborescens Mill. Var. natalensis Berger, which has widely been used in domestic medicines. Aloenin and magnesium lactate were elucidated to exhibit an inhibitory action on the gastric juice secretion of rats and was taken to also be helpful for arthritis and rheumatic fever. Various constituents other than the above bioactive substances were found in the leaves and the roots of the plant.

Leung, A. Y. (1977, June). Effective ingredients of Aloe vera. Drugs and Cosmetics, 34-35, 154-155.

Abstract: Effective ingredients of Aloe vera.

McKeown, E. C. (1983, June). Aloe vera: The quest for the “curative” missing link. Drug & Cosmetic Industry, 30ff.

Abstract: This article reviews what we currently know (or do not know) about the composition and analysis of aloe and examines the quest for the “curative” ingredient missing link.

Plaskett, L. G. (1996, November). The crucial importance of correct processing of Aloe vera. Aloe Vera Information Services (newsletter). Camelford, Cornwall, UK: Biomedical Information Services Ltd.

Abstract: The all-important biomedical activities of aloe juices and extracts depend critically upon applying strict rules of processing and handling. These determine whether or not the labile biochemicals in the living plant are successfully stabilized during manufacture and, subsequently, during distribution and storage.

Plaskett, L. G. (1997, May). The exudate compounds of Aloe and their likely benefits in the gel or whole leaf extract. Aloe Vera Information Services (newsletter). Camelford, Cornwall, UK: Biomedical Information Services Ltd.

Abstract: The compounds in Aloe vera exudate are often regarded as undesirable on account of their strong laxative action. Hence measures are usually taken to minimize the levels of these compounds in Aloe vera gels and juices that are intended for general health purposes. Such products do not generally cause any unwanted laxative effects. However, do ny small traces of these compounds which remain in the products actually contribute positively to the biomedical activities of Aloe vera gels and juices? Do some individual members of this group of compounds perhaps lack any laxative effect at all and only contribute desirable, health-giving effects? These questions are discussed in this newsletter.

Plaskett, L. G. (1996, July). The healing properties of Aloe. Aloe Vera Information Services(newsletter). Camelford, Cornwall, UK: Biomedical Information Services Ltd.

Abstract: Aloe vera contains Glucomannan, a special complex polysacchride composed largely of the sugar mannose. It interacts with special cell-surface receptors on those cells that repair damaged tissues, called fibroblasts, stimulating them and activating their faster growth and replication. Plant hormones in Aloe, called auxins and gibberellins, also accelerate healing by stimulating cell replication. These combined actions make Aloe a uniquely potent healing herb.

Plaskett, L. G. (1998, January). The Health and Medical Use of Aloe Vera. Tacoma, Washington: Life Sciences Press.

Abstract: Dr. Plaskett found that hundreds of scientific papers had been published over the years by researchers all around the world: almost the whole of this large body of work contained only positive reports on the effectiveness of Aloe.

Ritchey, C. R. (1955). Natural products from Aloe. Submitted to the Faculty of the Graduate College of the Oklahoma State University in partial fulfillment of the requirements for the Degree of Master of Science, July, 1972.

Abstract: The purpose of this study was to isolate and to identify a compound or compounds that occur in Aloe barbadensis. Qualitative analyses were performed using a combination of thin-layer chromatography, gas – liquid chromatography, and gas chromatography – mass spectrometry.

Shelton, R. M. (1991, October). Aloe vera: Its chemical and therapeutic properties. International Journal of Dermatology, 30(10), 679-683.

Abstract: In this review, the historical uses of Aloe will be highlighted and its chemical composition and biologic effects will be described.

Suga, T., and Hirata, T. (1983, June). The efficacy of the Aloe plants chemical constituents and biological activities. Cosmetics and Toiletries, 98, 105-108.

Abstract: The purpose of this paper is to review the usefulness of the aloe plants for use in dermatological preparations or for treatment of internal disorders.

Unknown. (n.d.). Comprehensive List of Ingredients for Aloe vera gel.

Abstract: Comprehensively lists the ingredients of Aloe vera gel.

Unknown. (n.d.). Analytical and reporting procedures.

Abstract: Four points of reference as reliable indicators in defining Aloe vera. Formula as a method for defining 100% aloe vera.

Waller, G. R., Mangiafico, S., and Ritchey, C. R. (1978). A chemical investigation of Aloe barbadensis Miller. Proceedings of the Oklahoma Academy of Science, 58, 69-76.

Abstract: Free amino acids, free monosaccharides and total saccharides released upon hydrolysis, sterols, and triterpenoids of the leaves of Aloe barbadensis Miller leaves were determined. Some seventeen amino acids, D-glucose, and D-mannose were present in the water-soluble fraction. Cholesterol, campesterol, β-sirosterol, and lupcol were found in substantial amounts in the lipid fraction. An unknown(s) alkaloid was detected using Dragendorff’s reagent.

Wang, Y. T., and Strong, K. J. (n.d.). Two-year study monitoring several physical and chemical properties of field-grown Aloe barbadensis Miller leaves. Texas A&M University.

Abstract: A two-year study on the properties of Aloe vera. The results of this study are being used by The International Aloe Science Council as the standard for what levels of various elements should be in Aloe vera for its certification program.

Yagi, A., Makino, K., and Nishioka, I. (1977). Studies on the constituents of Aloe saponaria Haw. II. The structures of tetrahydroanthracene derivatives, aloesaponol III and -IV. Chem. Pharm. Bull., 25(7), 1764-1770.

Abstract: This paper deals with structure elucidation of aloesaponol III and -IV and the elucidation of the absolute configuration of C 4 hydroxyl group in aloesaponol III and of C 3 hydroxyl group in aloesaponol I.

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